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Prestorage Leukocyte-Reduced Red Blood Cells PDF   Email

This form of RBCs requires special preparation by removing leukocytes (white blood cells) by filtration within 48 hours of donation. This is done because leukocytes remain in a unit of red blood cells during the storage process. These leukocytes, or the chemicals they produce, cytokines, have been implicated as a cause of blood recipients developing reactions to subsequent blood transfusions.


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